Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2153896 | 1.00 | BACE1 (0.75) | BACE1CTSD | |
| SCHEMBL15361835 | 0.87 | BACE1 (0.57) | BACE1CTSD | |
| SCHEMBL362674 | 0.85 | BACE1 (1.00) | BACE1 | |
| SCHEMBL362022 | 0.85 | BACE1 (1.00) | BACE1 | |
| SCHEMBL2153641 | 0.82 | BACE1 (0.74) | BACE1 | |
| SCHEMBL2153332 | 0.82 | BACE1 (0.55) | BACE1 | |
| SCHEMBL2153105 | 0.82 | BACE1 (0.55) | BACE1 | |
| SCHEMBL2154050 | 0.82 | BACE1 (0.75) | BACE1CTSD | |
| SCHEMBL2154463 | 0.82 | BACE1 (0.75) | BACE1CTSD | |
| SCHEMBL15678387 | 0.80 | BACE1 (0.90) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080176-A1 | PYRAZINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF NEUROLOGICAL DISORDERS | NOVARTIS AG (CH) | 2011-07-07 | — | — | WO | claimed |
| WO-2011080176-A1 | PYRAZINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF NEUROLOGICAL DISORDERS | NOVARTIS AG (CH) | 2011-07-07 | — | — | WO | disclosed |