Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25404663 | 0.80 | CHRM1 (0.45) | TBXAS1CHRM1KEAP1HDAC6FFAR1 | |
| SCHEMBL3930088 | 0.78 | NPSR1 (0.42) | CHRM1KEAP1HSD17B10PARP1PARP2 | |
| SCHEMBL926964 | 0.78 | HSD17B10 (0.45) | TBXAS1CHRM1KEAP1HDAC6FFAR1 | |
| SCHEMBL7532836 | 0.78 | CHRM1 (0.37) | TBXAS1CHRM1KEAP1HDAC6FFAR1 | |
| Hydrochloric Acid SCHEMBL25439022 | 0.77 | NPSR1 (0.41) | TBXAS1CHRM1KEAP1HSD17B10PARP1 | |
| SCHEMBL9183261 | 0.76 | CHRM1 (0.35) | TBXAS1CHRM1KEAP1HDAC6FFAR1 | |
| SCHEMBL20366143 | 0.76 | CHRM1 (0.38) | TBXAS1CHRM1KEAP1HDAC6FFAR1 | |
| SCHEMBL3005181 | 0.76 | CHRM1 (0.38) | TBXAS1CHRM1KEAP1PRKAG1PRKAA2 | |
| SCHEMBL2998729 | 0.74 | CHRM1 (0.37) | TBXAS1CHRM1PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL4880314 | 0.73 | FFAR1 (0.47) | CHRM1KEAP1FFAR1PRKAG1PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342194-A1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010052253-A1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-05-14 | — | — | WO | disclosed |
| US-4363815-A | Alpha hydroxyacids, alpha ketoacids and their use in treating skin conditions | YU RUEY J | 1982-12-14 | — | — | US | disclosed |