⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11166651 | 0.81 | — | — | |
| SCHEMBL1683579 | 0.72 | — | — | |
| SCHEMBL18537252 | 0.72 | — | — | |
| SCHEMBL29343773 | 0.72 | CYP2C19 (0.32) | — | |
| SCHEMBL21538113 | 0.70 | — | — | |
| Bromide SCHEMBL2356620 | 0.70 | CYP2C19 (0.31) | — | |
| SCHEMBL18025231 | 0.70 | HRH3 (0.36) | — | |
| SCHEMBL20561840 | 0.70 | — | — | |
| SCHEMBL14998979 | 0.68 | — | — | |
| SCHEMBL4190582 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240209015-A1 | METHODS OF SEQUENCING USING 3' BLOCKED NUCLEOTIDES | ILLUMINA, INC. | 2024-06-27 | — | — | US | disclosed |
| US-11787831-B2 | Nucleosides and nucleotides with 3′ acetal blocking group | ILLUMINA CAMBRIDGE LIMITED (GB) | 2023-10-17 | — | — | US | disclosed |
| US-20190330693-A1 | SINGLE FLUORESCENT DYE-BASED SEQUENCING METHOD | Qingdao MGI Tech Co., Ltd. (CN) | 2019-10-31 | — | — | US | disclosed |