Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 11/20 | 0.58 |
| ▸ | MC1R | Q01726 | 9/20 | 0.58 |
| ▸ | MC5R | P33032 | 1/20 | 0.41 |
| ▸ | MC3R | P41968 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 2/20 | 0.35 |
| ▸ | EDNRA | P25101 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20450381 | 0.96 | MC4R (0.62) | MC4RMC1RMC5RMC3REDNRB | |
| SCHEMBL1311323 | 0.96 | MC4R (0.62) | MC4RMC1RMC5RMC3REDNRB | |
| SCHEMBL2154280 | 0.95 | MC4R (0.53) | MC4RMC1RMC5RMC3RCHRM5 | |
| SCHEMBL2154100 | 0.94 | MC4R (0.56) | MC4RMC1RMC5RMC3REDNRB | |
| SCHEMBL1310742 | 0.94 | MC4R (0.53) | MC4RMC1RMC5RMC3RCHRM5 | |
| SCHEMBL20450393 | 0.94 | MC4R (0.53) | MC4RMC1RMC5RMC3RCHRM5 | |
| SCHEMBL1311346 | 0.93 | MC4R (0.54) | MC4RMC1RMC5RMC3RCHRM5 | |
| SCHEMBL20450394 | 0.93 | MC4R (0.54) | MC4RMC1RMC5RMC3RCHRM5 | |
| SCHEMBL2154756 | 0.93 | MC4R (0.68) | MC4RMC1RMC5RMC3RCHRM5 | |
| SCHEMBL20450417 | 0.89 | MC4R (0.55) | MC4RMC1RMC5RMC3REDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342194-A1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2011-07-13 | — | — | EP | claimed |
| EP-2342194-A1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2011-07-13 | — | — | EP | disclosed |