Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 18/20 | 0.49 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21541551 | 0.91 | MAPK1 (0.53) | MAPK1 | |
| SCHEMBL25970919 | 0.91 | MAPK1 (0.49) | MAPK1STAT6 | |
| SCHEMBL21541563 | 0.91 | MAPK1 (0.52) | MAPK1STAT6 | |
| SCHEMBL21557921 | 0.91 | MAPK1 (0.49) | MAPK1STAT6CHEK1 | |
| SCHEMBL21541562 | 0.89 | MAPK1 (0.54) | MAPK1 | |
| SCHEMBL20503855 | 0.87 | MAPK1 (0.46) | MAPK1STAT6CHEK1 | |
| SCHEMBL20503858 | 0.86 | MAPK1 (0.45) | MAPK1STAT6CHEK1 | |
| SCHEMBL21541548 | 0.85 | MAPK1 (0.59) | MAPK1 | |
| SCHEMBL21541557 | 0.85 | MAPK1 (0.57) | MAPK1 | |
| SCHEMBL20503875 | 0.85 | MAPK1 (0.46) | MAPK1STAT6CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3377491-B1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV DISCOVERY (FR) | 2019-11-13 | — | — | EP | claimed |