Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC1R | Q01726 | 8/20 | 0.52 |
| ▸ | MC4R | P32245 | 8/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 3/20 | 0.42 |
| ▸ | HRH1 | P35367 | 3/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1310190 | 0.95 | MC1R (0.48) | MC1RMC4RHDAC8OPRD1HRH2 | |
| Hydrochloric Acid SCHEMBL1310496 | 0.91 | MC1R (0.60) | MC1RMC4RHDAC8HRH2HRH1 | |
| Hydrochloric Acid SCHEMBL1310494 | 0.91 | MC1R (0.60) | MC1RMC4RHDAC8HRH2HRH1 | |
| SCHEMBL1310191 | 0.89 | MC1R (0.49) | MC1RMC4RHDAC8HRH2HRH1 | |
| SCHEMBL2149320 | 0.87 | MC1R (0.51) | MC1RMC4RHDAC8OPRD1HRH2 | |
| Trifluoroacetic Acid SCHEMBL1310217 | 0.87 | MC1R (0.57) | MC1RMC4RHRH2HRH1 | |
| SCHEMBL20450443 | 0.87 | MC1R (0.51) | MC1RMC4ROPRK1 | |
| SCHEMBL16445574 | 0.86 | MC1R (0.61) | MC1RMC4R | |
| Trifluoroacetic Acid SCHEMBL1312510 | 0.85 | MC1R (0.55) | MC1RMC4RHRH2HRH1 | |
| SCHEMBL1311899 | 0.82 | MC1R (0.47) | MC1RMC4RHDAC8OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342194-A1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010052253-A1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-05-14 | — | — | WO | disclosed |