SCHEMBL21544909

SCHEMBL21544909

CCCC[C@@H](Nc1ccc(C(=O)NCCC(=O)O)cc1)c1ccc(-c2nnc(C(F)(F)F)o2)cc1

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GCGR P47871 14/20 0.55
GLP1R P43220 2/20 0.51
GIPR P48546 2/20 0.51
GCG P01275 7/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21544912 1.00 GCGR (0.55) GCGRGLP1RGIPRGCG
SCHEMBL21544989 1.00 GCGR (0.55) GCGRGLP1RGIPRGCG
SCHEMBL21545051 0.95 GCGR (0.61) GCGRGLP1RGIPRGCG
SCHEMBL21544886 0.92 GCGR (0.50) GCGRGLP1RGIPRGCG
SCHEMBL21562711 0.90 GCGR (0.45) GCGRGLP1RGIPRGCG
SCHEMBL21545043 0.90 GCGR (0.45) GCGRGLP1RGIPRGCG
SCHEMBL21562708 0.90 GCGR (0.45) GCGRGLP1RGIPRGCG
SCHEMBL21544906 0.89 GCGR (0.59) GCGRGLP1RGIPRGCG
SCHEMBL21562702 0.89 GCGR (0.59) GCGRGLP1RGIPRGCG
SCHEMBL21544961 0.88 GCGR (0.59) GCGRGCG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3573611-B1 AMIDE COMPOUNDS AND USE THEREOF ALPHALA CO LTD (TW) 2022-01-12 EP claimed
US-10882837-B2 Amide compounds and use thereof ALPHALA CO., LTD. (TW) 2021-01-05 US claimed
EP-3573611-B1 AMIDE COMPOUNDS AND USE THEREOF ALPHALA CO LTD (TW) 2022-01-12 EP disclosed
EP-3573611-B1 AMIDE COMPOUNDS AND USE THEREOF ALPHALA CO LTD (TW) 2022-01-12 EP disclosed
US-10882837-B2 Amide compounds and use thereof ALPHALA CO., LTD. (TW) 2021-01-05 US disclosed
US-10882837-B2 Amide compounds and use thereof ALPHALA CO., LTD. (TW) 2021-01-05 US disclosed
US-20190345118-A1 AMIDE COMPOUNDS AND USE THEREOF ALPHALA CO., LTD. (TW) 2019-11-14 US disclosed
US-20190345118-A1 AMIDE COMPOUNDS AND USE THEREOF ALPHALA CO., LTD. (TW) 2019-11-14 US disclosed
CN-110234318-A Amide compound and its application 昊运股份有限公司 2019-09-13 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10882837-B2 Amide compounds and use thereof GLP1R, IAPP, GCG GCGR 5/4885GLP1R 1/4885GIPR 6/4885
US-20190345118-A1 AMIDE COMPOUNDS AND USE THEREOF GLP1R, IAPP, GCG GCGR 5/4885GLP1R 1/4885GIPR 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.