Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 9/20 | 0.41 |
| ▸ | HTR1A | P08908 | 6/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21147732 | 1.00 | HRH3 (0.47) | HRH3HTR7HTR1AHRH1DRD3 | |
| SCHEMBL21148138 | 1.00 | HRH3 (0.47) | HRH3HTR7HTR1AHRH1DRD3 | |
| SCHEMBL17263959 | 0.98 | HRH3 (0.48) | HRH3HTR7HTR1AHRH1DRD3 | |
| SCHEMBL13394402 | 0.95 | HRH3 (0.44) | HRH3HTR7HTR1AHRH1DRD3 | |
| SCHEMBL96768 | 0.95 | HRH3 (0.44) | HRH3HTR7HTR1AHRH1DRD3 | |
| SCHEMBL7740824 | 0.91 | NPC1 (0.47) | HRH3NPC1GBA1 | |
| SCHEMBL96616 | 0.91 | HRH3 (0.40) | HRH3HTR7HTR1AHRH1DRD3 | |
| SCHEMBL13568869 | 0.91 | HRH3 (0.40) | HRH3HTR7HTR1AHRH1DRD3 | |
| SCHEMBL96767 | 0.87 | GBA1 (0.44) | HRH3HTR7HTR1AHTR2ADRD2 | |
| SCHEMBL13394401 | 0.87 | GBA1 (0.44) | HRH3HTR7HTR1AHTR2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564236-A1 | PROCESS FOR PREPARING 4-SUBSTITUTED-1-(2-METHOXYETHYL)PYRROLIDIN-3-AMINE DERIVATIVES | Array Biopharma, Inc. (US) | 2019-11-06 | — | — | EP | disclosed |