Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034128 | 0.82 | HCAR2 (0.62) | HCAR2POLBNPC1RAB9AKMT2A | |
| SCHEMBL1800827 | 0.79 | HCAR2 (0.58) | HCAR2POLBNPC1RAB9AKMT2A | |
| Bicarbonate SCHEMBL6633930 | 0.77 | HCAR2 (0.55) | HCAR2POLBNPC1RAB9AKMT2A | |
| Bicarbonate SCHEMBL6633929 | 0.77 | HCAR2 (0.55) | HCAR2POLBNPC1RAB9AKMT2A | |
| SCHEMBL222184 | 0.75 | — | — | |
| Bicarbonate SCHEMBL6633927 | 0.75 | HCAR2 (0.58) | HCAR2POLBNPC1RAB9AKMT2A | |
| SCHEMBL11489630 | 0.74 | — | — | |
| SCHEMBL353474 | 0.74 | — | — | |
| SCHEMBL1797269 | 0.74 | — | — | |
| SCHEMBL11489629 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3350175-B1 | NON-STEROIDAL GLUCOCORTICOID RECEPTOR MODULATORS FOR LOCAL DRUG DELIVERY | LEO PHARMA AS (DK) | 2019-11-06 | — | — | EP | disclosed |