Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | ACACA | Q13085 | 2/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25144989 | 0.77 | NOTUM (0.44) | TSHRNOTUMMAPTALDH1A1HPGD | |
| SCHEMBL21366302 | 0.72 | CNR2 (0.37) | TSHRNOTUMMAPTALDH1A1HPGD | |
| SCHEMBL25986910 | 0.70 | NOTUM (0.39) | NOTUMMAPTALDH1A1RAB9AHPGD | |
| SCHEMBL12469961 | 0.69 | PPARA (0.48) | TSHRNOTUM | |
| SCHEMBL21808096 | 0.69 | SMN1; SMN2 (0.39) | ACACBACACAAPOBEC3AAPOBEC3GTSHR | |
| SCHEMBL764028 | 0.68 | — | — | |
| SCHEMBL12469959 | 0.67 | NOTUM (0.33) | NOTUM | |
| SCHEMBL91541 | 0.66 | NOTUM (0.68) | ACACBACACATSHRNOTUMMAPT | |
| SCHEMBL14873222 | 0.66 | ACACB (0.57) | ACACBACACAMAPTALDH1A1RAB9A | |
| SCHEMBL12906161 | 0.65 | NOTUM (0.59) | TSHRNOTUMMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564239-A1 | ARYL HYDROCARBON RECEPTOR MODULATOR | Shenzhen Immunova Pharmaceutical Co., Ltd. (CN) | 2019-11-06 | — | — | EP | disclosed |