Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 8/20 | 0.36 |
| ▸ | FAP | Q12884 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 2/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24503644 | 0.80 | DPP7 (0.44) | DPP7DPP4FAPPOLBEPHX1 | |
| SCHEMBL11675346 | 0.78 | DPP7 (0.46) | DPP7KDM4EMEN1KMT2APABPC1 | |
| SCHEMBL26163004 | 0.77 | KDM4E (0.56) | DPP7KDM4EPABPC1DPP4FAP | |
| SCHEMBL19721644 | 0.77 | KDM4E (0.56) | DPP7KDM4EPABPC1DPP4FAP | |
| SCHEMBL1044361 | 0.77 | — | — | |
| SCHEMBL11678027 | 0.76 | DPP7 (0.42) | DPP7KDM4EMEN1KMT2APABPC1 | |
| SCHEMBL25481378 | 0.75 | KDM4E (0.47) | DPP7KDM4EMEN1KMT2APABPC1 | |
| SCHEMBL8552632 | 0.75 | KMT2A (0.50) | DPP7KDM4EMEN1KMT2ADPP4 | |
| SCHEMBL15342527 | 0.74 | — | — | |
| Water SCHEMBL13278005 | 0.74 | KDM4E (0.54) | DPP7KDM4EPABPC1DPP4FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564253-A1 | ANTIDEPRESSANT COMPOUND AND PREPARATION METHOD AND APPLICATION THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2019-11-06 | — | — | EP | disclosed |