Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15429049 | 1.00 | CYP3A4 (0.47) | CYP3A4TSHRLPAR3LPAR1LPAR2 | |
| SCHEMBL17342350 | 0.87 | TSHR (0.42) | CYP3A4TSHRLPAR3LPAR1LPAR2 | |
| SCHEMBL777791 | 0.86 | — | — | |
| SCHEMBL18686721 | 0.86 | PPARD (0.42) | CYP3A4TSHRLPAR3LPAR1LPAR2 | |
| SCHEMBL17626507 | 0.84 | LPAR3 (0.41) | CYP3A4TSHRLPAR3LPAR1LPAR2 | |
| SCHEMBL17626482 | 0.84 | MEN1 (0.42) | CYP3A4TSHRLPAR3LPAR1LPAR2 | |
| SCHEMBL17626598 | 0.84 | LPAR3 (0.41) | CYP3A4TSHRLPAR3LPAR1LPAR2 | |
| SCHEMBL10138513 | 0.82 | LPAR3 (0.56) | CYP3A4TSHRLPAR3LPAR1LPAR2 | |
| SCHEMBL2046368 | 0.82 | LPAR3 (0.56) | CYP3A4TSHRLPAR3LPAR1LPAR2 | |
| SCHEMBL2522278 | 0.82 | CYP3A4 (0.50) | CYP3A4TSHRLPAR3LPAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2895200-B1 | MULTIMERIC OLIGONUCLEOTIDE COMPOUNDS | TRANSLATE BIO MA INC (US) | 2019-11-06 | — | — | EP | disclosed |