Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22722372 | 0.89 | MKNK1 (0.77) | MKNK1MKNK2 | |
| SCHEMBL21554403 | 0.86 | MKNK1 (0.74) | MKNK1MKNK2 | |
| SCHEMBL22722381 | 0.81 | MKNK1 (1.00) | MKNK1MKNK2 | |
| SCHEMBL18803507 | 0.80 | MKNK1 (1.00) | MKNK1MKNK2 | |
| SCHEMBL21554278 | 0.79 | MKNK1 (0.78) | MKNK1MKNK2 | |
| SCHEMBL21554385 | 0.78 | MKNK1 (0.71) | MKNK1MKNK2 | |
| SCHEMBL21554422 | 0.77 | MKNK1 (0.62) | MKNK1MKNK2 | |
| SCHEMBL20479136 | 0.76 | MKNK1 (0.76) | MKNK1MKNK2 | |
| SCHEMBL22722410 | 0.73 | MKNK1 (1.00) | MKNK1MKNK2 | |
| SCHEMBL20479141 | 0.71 | MKNK1 (1.00) | MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564235-A1 | SUBSTITUTED AROMATIC N-HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MITOGEN-ACTIVATED PROTEIN KINASE INTERACTING KINASE 1 (MNK1) AND 2 (MNK2) | Northwestern University (US) | 2019-11-06 | — | — | EP | disclosed |