Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5178494 | 1.00 | TP53 (0.56) | TP53ALDH1A1CYP2C19ALOX15CYP2C9 | |
| SCHEMBL5179413 | 0.98 | TP53 (0.58) | TP53ALDH1A1CYP2C19ALOX15CYP2C9 | |
| SCHEMBL4442531 | 0.93 | TP53 (0.55) | TP53ALDH1A1CYP2C19ALOX15CYP2C9 | |
| SCHEMBL4126962 | 0.90 | TP53 (0.70) | TP53CYP2C19ALOX15CYP2C9TSHR | |
| SCHEMBL4111330 | 0.90 | TP53 (0.70) | TP53CYP2C19ALOX15CYP2C9TSHR | |
| SCHEMBL5179051 | 0.90 | TP53 (0.54) | TP53ALDH1A1CYP2C19ALOX15CYP2C9 | |
| SCHEMBL4125305 | 0.89 | TP53 (0.72) | TP53ALDH1A1CYP2C19ALOX15CYP2C9 | |
| SCHEMBL4135092 | 0.83 | TP53 (0.69) | TP53ALDH1A1CYP2C19ALOX15CYP2C9 | |
| SCHEMBL11648834 | 0.80 | TP53 (0.39) | TP53ALDH1A1GPR84FFAR1HIF1A | |
| SCHEMBL6504045 | 0.77 | CYP1A2 (0.39) | TP53ALDH1A1CYP2C19CYP2C9GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3082924-B1 | PATIENT INTERFACE | KONINKLIJKE PHILIPS NV (NL) | 2019-11-13 | — | — | EP | disclosed |