Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29776554 | 0.85 | POLB (0.49) | POLBHRH3TLR8HRH4NUDT1 | |
| SCHEMBL27814382 | 0.83 | TLR8 (0.46) | POLBHRH3TLR8HRH4NUDT1 | |
| SCHEMBL2031722 | 0.82 | POLB (0.50) | POLBHRH3TLR8HRH4NUDT1 | |
| SCHEMBL2036582 | 0.82 | POLB (0.46) | POLBHRH3TLR8HRH4NUDT1 | |
| SCHEMBL2035539 | 0.82 | POLB (0.46) | POLBHRH3TLR8HRH4NUDT1 | |
| SCHEMBL2036679 | 0.82 | POLB (0.46) | POLBHRH3TLR8HRH4NUDT1 | |
| SCHEMBL83993 | 0.81 | POLB (0.56) | POLBHRH3TLR8HRH4NUDT1 | |
| SCHEMBL29718738 | 0.81 | POLB (0.56) | POLBHRH3TLR8HRH4NUDT1 | |
| SCHEMBL2033996 | 0.79 | POLB (0.54) | POLBHRH3TLR8HRH4NUDT1 | |
| SCHEMBL2033811 | 0.78 | POLB (0.53) | POLBHRH3TLR8HRH4NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567029-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2019-11-13 | — | — | EP | disclosed |