Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.48 |
| ▸ | CCR1 | P32246 | 13/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | ACTR2 | P61160 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | FPR3 | P25089 | 1/20 | 0.41 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4500409 | 0.86 | MAPK14 (0.52) | MAPK14CCR1MAPK11MAPK13MAPK12 | |
| SCHEMBL4500411 | 0.86 | MAPK14 (0.52) | MAPK14CCR1MAPK11MAPK13MAPK12 | |
| SCHEMBL4495934 | 0.84 | MAPK14 (0.56) | MAPK14CCR1MAPK11MAPK13MAPK12 | |
| SCHEMBL4495937 | 0.84 | MAPK14 (0.56) | MAPK14CCR1MAPK11MAPK13MAPK12 | |
| SCHEMBL4512803 | 0.83 | MAPK14 (0.53) | MAPK14CCR1MAPK11MAPK13MAPK12 | |
| SCHEMBL4512801 | 0.83 | MAPK14 (0.53) | MAPK14CCR1MAPK11MAPK13MAPK12 | |
| SCHEMBL4500428 | 0.81 | CCR1 (0.51) | MAPK14CCR1PTGDR2FPR3GPR65 | |
| SCHEMBL4500424 | 0.81 | CCR1 (0.51) | MAPK14CCR1PTGDR2FPR3GPR65 | |
| SCHEMBL22764065 | 0.77 | MAPK14 (0.57) | MAPK14CCR1MAPK11MAPK13MAPK12 | |
| SCHEMBL4504045 | 0.76 | MAPK14 (0.55) | MAPK14CCR1MAPK11MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3081568-B1 | COMPOSITIONS AND METHODS FOR TREATING ALZHEIMER'S DISEASE | EIP PHARMA LLC (US) | 2019-11-13 | — | — | EP | disclosed |