Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18892014 | 0.93 | MAPK1 (0.66) | MAPK1 | |
| SCHEMBL18891662 | 0.83 | MAPK1 (0.70) | MAPK1 | |
| SCHEMBL18892271 | 0.83 | MAPK1 (0.74) | MAPK1 | |
| SCHEMBL18892270 | 0.83 | MAPK1 (0.68) | MAPK1 | |
| SCHEMBL18860577 | 0.82 | MAPK1 (0.79) | MAPK1 | |
| SCHEMBL18892012 | 0.81 | MAPK1 (0.69) | MAPK1 | |
| SCHEMBL21557756 | 0.80 | MAPK1 (0.44) | MAPK1 | |
| SCHEMBL18892011 | 0.80 | MAPK1 (0.71) | MAPK1 | |
| SCHEMBL18891663 | 0.79 | MAPK1 (0.69) | MAPK1 | |
| SCHEMBL18892099 | 0.78 | MAPK1 (0.78) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3377491-B1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV DISCOVERY (FR) | 2019-11-13 | — | — | EP | disclosed |