Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 6/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20503927 | 0.83 | MAPK1 (0.49) | MAPK1BRD4METAP2 | |
| SCHEMBL21557694 | 0.77 | SLC6A2 (0.38) | METAP2 | |
| SCHEMBL21557634 | 0.76 | — | — | |
| SCHEMBL20504001 | 0.74 | MAPK1 (0.43) | MAPK1BRD4METAP2 | |
| SCHEMBL21541546 | 0.73 | BRD4 (0.41) | MAPK1BRD4METAP2 | |
| SCHEMBL20504242 | 0.73 | MAPK1 (0.49) | MAPK1BRD4METAP2 | |
| SCHEMBL20503958 | 0.73 | MAPK1 (0.49) | MAPK1BRD4METAP2 | |
| SCHEMBL20504101 | 0.73 | BRD4 (0.41) | MAPK1BRD4METAP2 | |
| SCHEMBL20503996 | 0.73 | MAPK1 (0.49) | MAPK1BRD4METAP2 | |
| SCHEMBL20504100 | 0.73 | BRD4 (0.41) | MAPK1BRD4METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3377491-B1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV DISCOVERY (FR) | 2019-11-13 | — | — | EP | disclosed |