⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24461760 | 1.00 | — | — | |
| SCHEMBL26343165 | 1.00 | — | — | |
| SCHEMBL14017877 | 0.71 | — | — | |
| SCHEMBL23096837 | 0.71 | — | — | |
| SCHEMBL19010422 | 0.69 | — | — | |
| SCHEMBL22876842 | 0.69 | — | — | |
| SCHEMBL18239353 | 0.67 | — | — | |
| SCHEMBL19291874 | 0.67 | — | — | |
| SCHEMBL18445839 | 0.65 | — | — | |
| SCHEMBL19012774 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019215470-A1 | USE OF GUANABENZ OR DERIVATES THEREOF FOR THE TREATMENT OF TYPE I IFN-DEPENDENT PATHOLOGIES | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2019-11-14 | — | — | WO | disclosed |