⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13077659 | 0.70 | — | — | |
| SCHEMBL3500359 | 0.69 | — | — | |
| SCHEMBL2375307 | 0.69 | — | — | |
| SCHEMBL1849267 | 0.67 | — | — | |
| SCHEMBL4115393 | 0.67 | — | — | |
| SCHEMBL4115389 | 0.67 | — | — | |
| SCHEMBL27274951 | 0.65 | — | — | |
| Ethane SCHEMBL29047756 | 0.64 | — | — | |
| SCHEMBL195729 | 0.64 | — | — | |
| SCHEMBL7518104 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973082-B2 | Substituted aryloxy alkylamines and their use as monoamine neurotransmitter re-uptake inhibitors | NEUROSEARCH A/S (DK) | 2011-07-05 | — | — | US | disclosed |
| US-20090215905-A1 | Novel substituted aryloxy alkylamines and their use as monoamine neurotransmitter re-uptake inhibitors | ANIONA APS (DK) | 2009-08-27 | — | — | US | disclosed |
| US-20090023772-A1 | Novel substituted heteroaryloxy alkylamines and their use as monoamine neurotransmitter re-uptake inhibitors | NEUROSEARCH A/S (DK) | 2009-01-22 | — | — | US | disclosed |
| EP-1786778-A1 | NOVEL SUBSTITUTED HETEROARYLOXY ALKYLAMINES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2007-05-23 | — | — | EP | disclosed |
| EP-1784381-A1 | NOVEL SUBSTITUTED ARYLOXY ALKYLAMINES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006021564-A1 | NOVEL SUBSTITUTED ARYLOXY ALKYLAMINES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2006-03-02 | — | — | WO | disclosed |
| WO-2006021565-A1 | NOVEL SUBSTITUTED HETEROARYLOXY ALKYLAMINES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2006-03-02 | — | — | WO | disclosed |