⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31246068 | 1.00 | — | — | |
| SCHEMBL21831505 | 1.00 | — | — | |
| SCHEMBL19948222 | 1.00 | — | — | |
| SCHEMBL31246106 | 1.00 | — | — | |
| SCHEMBL6888398 | 1.00 | — | — | |
| SCHEMBL21050730 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL23646092 | 0.98 | GBA1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL13732781 | 0.98 | GBA1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL21050971 | 0.98 | GBA1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL30900009 | 0.98 | GBA1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114040914-B | Quinazolinone derivative, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-114040914-A | Quinazolinone derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2022-02-11 | — | — | CN | disclosed |
| US-20210221823-A1 | TETRACYCLIC HETEROARYL COMPOUNDS | ASTRAZENECA AB (SE) | 2021-07-22 | — | — | US | disclosed |
| WO-2019215203-A1 | TETRACYCLIC HETEROARYL COMPOUNDS | ASTRAZENECA AB (SE) | 2019-11-14 | — | — | WO | disclosed |