SCHEMBL21564381

SCHEMBL21564381

CNC(=O)NCC1CCN(Cc2cc(Oc3cnc(N4CCN(CC=O)CC4)nc3)nc(-c3cc(Cl)cc(Cl)c3)c2)CC1

nearest known ligand 0.73

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 20/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21564442 0.93 FURIN (0.83) FURIN
SCHEMBL21550737 0.93 FURIN (0.78) FURIN
SCHEMBL29928688 0.93 FURIN (0.78) FURIN
SCHEMBL21551001 0.93 FURIN (0.78) FURIN
SCHEMBL29928242 0.93 FURIN (0.78) FURIN
SCHEMBL28547452 0.93 FURIN (0.75) FURIN
SCHEMBL26077347 0.93 FURIN (0.70) FURIN
SCHEMBL21551504 0.92 FURIN (0.72) FURIN
SCHEMBL21553742 0.92 FURIN (0.73) FURIN
SCHEMBL21553780 0.92 FURIN (0.80) FURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019215341-A1 FURIN INHIBITORS GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2019-11-14 — — WO disclosed
US-9388132-B2 Isobaric tandem mass tags for quantitative proteomics and peptidomics WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2016-07-12 — — US disclosed
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