SCHEMBL21564395

SCHEMBL21564395

CCOC(=O)CCN1CCN(c2ncc(Oc3cc(COC)cc(-c4cc(Cl)cc(Cl)c4)n3)cn2)CC1

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 19/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21551546 0.92 FURIN (0.60) FURIN
SCHEMBL21551178 0.91 FURIN (0.57) FURIN
SCHEMBL21551275 0.88 FURIN (0.63) FURIN
SCHEMBL21550898 0.88 FURIN (0.65) FURIN
SCHEMBL21551716 0.88 FURIN (0.64) FURIN
SCHEMBL21551435 0.86 FURIN (0.61) FURIN
SCHEMBL21551308 0.85 FURIN (0.64) FURIN
SCHEMBL21564549 0.85 FURIN (0.59) FURIN
SCHEMBL21551081 0.84 FURIN (0.59) FURIN
SCHEMBL21551517 0.84 FURIN (0.85) FURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019215341-A1 FURIN INHIBITORS GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2019-11-14 — — WO disclosed
US-9388132-B2 Isobaric tandem mass tags for quantitative proteomics and peptidomics WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2016-07-12 — — US disclosed
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