Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 19/20 | 0.58 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29890972 | 0.88 | FURIN (0.71) | FURIN | |
| SCHEMBL21551340 | 0.88 | FURIN (0.71) | FURIN | |
| SCHEMBL21553838 | 0.87 | FURIN (0.61) | FURIN | |
| SCHEMBL21553837 | 0.87 | FURIN (0.61) | FURIN | |
| SCHEMBL29890831 | 0.87 | FURIN (0.69) | FURIN | |
| SCHEMBL21550886 | 0.87 | FURIN (0.69) | FURIN | |
| SCHEMBL29891352 | 0.86 | FURIN (0.68) | FURIN | |
| SCHEMBL21551073 | 0.86 | FURIN (0.68) | FURIN | |
| SCHEMBL21551398 | 0.86 | FURIN (0.56) | FURINGPR119 | |
| SCHEMBL21564420 | 0.86 | FURIN (0.69) | FURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3790871-B1 | FURIN INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2024-01-24 | — | — | EP | disclosed |
| WO-2019215341-A1 | FURIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-11-14 | — | — | WO | disclosed |