SCHEMBL21564535

SCHEMBL21564535

CC1CCCN(Cc2cc(Oc3cnc(N4CCN(CCC(=O)O)CC4)nc3)nc(-c3cc(Cl)cc(Cl)c3)c2)CC1

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 20/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21564704 0.90 FURIN (0.78) FURIN
SCHEMBL27056074 0.89 FURIN (0.80) FURIN
SCHEMBL21564382 0.88 FURIN (0.75) FURIN
SCHEMBL24872364 0.88 FURIN (0.81) FURIN
SCHEMBL21550620 0.88 FURIN (0.81) FURIN
SCHEMBL21550619 0.88 FURIN (0.81) FURIN
SCHEMBL21550616 0.88 FURIN (0.81) FURIN
SCHEMBL21550809 0.88 FURIN (0.74) FURIN
SCHEMBL29928110 0.88 FURIN (0.74) FURIN
SCHEMBL21550715 0.87 FURIN (1.00) FURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3790871-B1 FURIN INHIBITORS GLAXOSMITHKLINE IP DEV LTD (GB) 2024-01-24 — — EP disclosed
WO-2019215341-A1 FURIN INHIBITORS GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2019-11-14 — — WO disclosed
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