SCHEMBL2156532

SCHEMBL2156532

C=CCN(CCCCCCCC)CCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
DNM1 Q05193 3/20 0.44
ALDH1A1 P00352 1/20 0.40
KCNH2 Q12809 6/20 0.39
FAAH O00519 1/20 0.38
THRB P10828 1/20 0.38
ZDHHC20 Q5W0Z9 1/20 0.37
ZDHHC2 Q9UIJ5 1/20 0.37
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
ADH1C P00326 1/20 0.35
ADH1A P07327 1/20 0.35
ADH4 P08319 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8423278 1.00 TSHR (0.48) TSHRDNM1ALDH1A1KCNH2FAAH
SCHEMBL8421983 1.00 TSHR (0.48) TSHRDNM1ALDH1A1KCNH2FAAH
SCHEMBL22157373 1.00 TSHR (0.48) TSHRDNM1ALDH1A1KCNH2FAAH
SCHEMBL28760238 1.00 TSHR (0.48) TSHRDNM1ALDH1A1KCNH2FAAH
SCHEMBL11233672 1.00 TSHR (0.48) TSHRDNM1ALDH1A1KCNH2FAAH
SCHEMBL6159782 1.00 TSHR (0.48) TSHRDNM1ALDH1A1KCNH2FAAH
SCHEMBL28485740 1.00 TSHR (0.48) TSHRDNM1ALDH1A1KCNH2FAAH
SCHEMBL8850444 0.98 TSHR (0.46) TSHRDNM1ALDH1A1KCNH2FAAH
SCHEMBL22157363 0.98 TSHR (0.46) TSHRDNM1ALDH1A1KCNH2FAAH
SCHEMBL4140633 0.98 TSHR (0.44) TSHRDNM1ALDH1A1KCNH2FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2516474-B9 MODIFIED POLYMER COMPOSITIONS STYRON EUROPE GMBH (CH) 2015-04-08 EP disclosed
EP-2516474-B9 MODIFIED POLYMER COMPOSITIONS STYRON EUROPE GMBH (CH) 2015-04-08 EP disclosed
US-8921502-B2 Modified polymer compositions STYRON EUROPE GMBH (CH) 2014-12-30 US disclosed
US-8921502-B2 Modified polymer compositions STYRON EUROPE GMBH (CH) 2014-12-30 US disclosed
US-8895684-B2 Modified polymer compositions STYRON EUROPE GMBH (CH) 2014-11-25 US disclosed
US-8895684-B2 Modified polymer compositions STYRON EUROPE GMBH (CH) 2014-11-25 US disclosed
US-8895684-B2 Modified polymer compositions STYRON EUROPE GMBH (CH) 2014-11-25 US disclosed
EP-2516478-B1 MODIFIED POLYMER COMPOSITIONS STYRON EUROPE GMBH (CH) 2014-06-11 EP disclosed
EP-2516478-B1 MODIFIED POLYMER COMPOSITIONS STYRON EUROPE GMBH (CH) 2014-06-11 EP disclosed
EP-2516474-B1 MODIFIED POLYMER COMPOSITIONS STYRON EUROPE GMBH (CH) 2013-11-06 EP disclosed
WO-2011079922-A1 MODIFIED POLYMER COMPOSITIONS STYRON EUROPE GMBH (CH) 2011-07-07 WO disclosed
WO-2011079922-A1 MODIFIED POLYMER COMPOSITIONS STYRON EUROPE GMBH (CH) 2011-07-07 WO disclosed
US-20090035696-A1 PHOTORESIST COMPOSITION KYOWA HAKKO CHEMICAL CO., LTD. (JP) 2009-02-05 US disclosed
US-20030138846-A1 Solid phase supports AKZO NOBEL N.V. (NL) 2003-07-24 US disclosed
US-6486354-B1 Solid phase supports AKZO NOBEL N.V. (NL) 2002-11-26 US disclosed
EP-0454622-B1 Alkenyl substituted stabilizers CIBA GEIGY AG (CH) 1999-10-13 EP disclosed
US-5268114-A Oxidation, heat and radiation resistance; for lubricating oil CIBA-GEIGY CORPORATION (US) 1993-12-07 US disclosed
US-5162408-A Polypropylene CIBA-GEIGY CORPORATION (US) 1992-11-10 US disclosed
US-5081300-A N-alkenyl substituted amine-N-oxide stabilizers CIBA-GEIGY CORPORATION (US) 1992-01-14 US disclosed
EP-0454622-A1 Alkenyl substituted stabilizers CIBA-GEIGY AG (CH) 1991-10-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030138846-A1 Solid phase supports NES, CCNY, CCNA2 TSHR 4277/4885DNM1 3962/4885ALDH1A1 1873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.