SCHEMBL21565663

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23116284	1.00	KCNH2 (0.81)	KCNH2SLC16A3KDM1AMEN1KMT2A
	SCHEMBL23116308	0.91	SLC16A3 (0.81)	KCNH2SLC16A3AXLFLT3TYRO3
	SCHEMBL21565662	0.91	SLC16A3 (0.81)	KCNH2SLC16A3AXLFLT3TYRO3
	SCHEMBL21565517	0.91	KCNH2 (0.77)	KCNH2SLC16A3KDM1AMEN1KMT2A
	SCHEMBL23116367	0.91	KCNH2 (0.77)	KCNH2SLC16A3KDM1AMEN1KMT2A
	SCHEMBL23116299	0.90	KCNH2 (1.00)	KCNH2SLC16A3KDM1AMEN1KMT2A
	SCHEMBL21565528	0.90	KCNH2 (1.00)	KCNH2SLC16A3KDM1AMEN1KMT2A
	SCHEMBL21550733	0.88	KCNH2 (0.77)	KCNH2SLC16A3KDM1AMEN1KMT2A
	SCHEMBL21550735	0.88	KCNH2 (0.77)	KCNH2SLC16A3KDM1AMEN1KMT2A
	SCHEMBL23116327	0.87	KCNH2 (0.76)	KCNH2SLC16A3KDM1AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.