Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29727863 | 1.00 | CYP1A2 (0.57) | CYP1A2TSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL30122458 | 0.91 | CYP1A2 (0.52) | CYP1A2TSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL1198631 | 0.91 | CYP1A2 (0.52) | CYP1A2TSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL2442735 | 0.89 | CYP1A2 (0.53) | CYP1A2TSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL6036755 | 0.87 | CYP1A2 (0.52) | CYP1A2TSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL8793429 | 0.87 | CYP1A2 (0.52) | CYP1A2TSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL8053279 | 0.86 | TSHR (0.58) | CYP1A2TSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL864403 | 0.84 | CYP1A2 (0.59) | CYP1A2TSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL2374034 | 0.82 | TSHR (0.52) | CYP1A2TSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL10179453 | 0.82 | CYP1A2 (0.47) | CYP1A2TSHRALDH1A1CYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12312363-B2 | Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-p53 inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2025-05-27 | — | — | US | disclosed |
| CN-118084710-A | Kv7 potassium ion channel opener, and pharmaceutical composition and application thereof | 青岛海枢康制药有限公司 | 2024-05-28 | — | — | CN | disclosed |
| US-20240109913-A1 | NEW SPIRO[3H-INDOLE-3,2'-PYRROLIDIN]-2(1H)-ONE COMPOUNDS AND DERIVATIVES AS MDM2-P53 INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2024-04-04 | — | — | US | disclosed |
| CN-113861110-B | Polysubstituted sulfonamide compound, preparation method and medical application thereof | 中国药科大学 | 2024-03-01 | — | — | CN | disclosed |
| EP-3625215-B1 | FORMIMIDAMIDINE COMPOUNDS USEFUL AGAINST PHYTOPATHOGENIC MICROORGANISMS | PI INDUSTRIES LTD (IN) | 2023-09-13 | — | — | EP | disclosed |
| EP-3625215-B1 | FORMIMIDAMIDINE COMPOUNDS USEFUL AGAINST PHYTOPATHOGENIC MICROORGANISMS | PI INDUSTRIES LTD (IN) | 2023-09-13 | — | — | EP | disclosed |
| CN-116670127-A | EGFR inhibitors and compositions and uses thereof | 贝达药业股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-113072741-B | Environment-friendly p-phenylenediamine anti-aging agent and preparation method and application thereof | 怡维怡橡胶研究院有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-113861110-A | Polysubstituted sulfonamide compound, preparation method and medical application thereof | 中国药科大学 | 2021-12-31 | — | — | CN | disclosed |
| CN-113072741-A | Environment-friendly p-phenylenediamine anti-aging agent and preparation method and application thereof | 怡维怡橡胶研究院有限公司 | 2021-07-06 | — | — | CN | disclosed |
| EP-1150944-B1 | N2-PHENYLAMIDINE DERIVATIVES | BAYER CROPSCIENCE GMBH (DE) | 2003-08-20 | — | — | EP | disclosed |
| US-20030088050-A1 | Substituted poly(arylenevinylenes), process for their preparation, and their use in electroluminescent elements | MERCK PATENT GMBH (DE) | 2003-05-08 | — | — | US | disclosed |
| US-20030008884-A1 | Fungicidal phenyl (thio) urea and phenyl (thio) carbamate derivatives | AVENTIS CROPSCIENCE S.A. | 2003-01-09 | — | — | US | disclosed |
| US-20020064680-A1 | Substituted poly(arylene vinylenes), method for producing the same, and their use in electroluminescent elements | AXIVA GMBH (DE) | 2002-05-30 | — | — | US | disclosed |
| CN-1342137-A | N2 phenylamidine derivatives | AFINDY AGRICULTURAL SCIENCES G (DE) | 2002-03-27 | — | — | CN | disclosed |
| EP-1178039-A1 | Derivatives of phenyl(thio)urea and phenyl(thio)carbamate fungicides | AVENTIS CROPSCIENCE S.A. (FR) | 2002-02-06 | — | — | EP | disclosed |
| EP-1150944-A1 | N2-PHENYLAMIDINE DERIVATIVES | Aventis CropScience GmbH (DE) | 2001-11-07 | — | — | EP | disclosed |
| EP-1029019-A1 | SUBSTITUTED POLY(ARYLENE VINYLENES), METHOD FOR PRODUCING THE SAME, AND THEIR USE IN ELECTROLUMINESCENT ELEMENTS | Axiva GmbH (DE) | 2000-08-23 | — | — | EP | disclosed |
| WO-2000046184-A1 | N2-PHENYLAMIDINE DERIVATIVES | AVENTIS CROPSCIENCE GMBH (FR) | 2000-08-10 | — | — | WO | disclosed |
| WO-1999024526-A1 | SUBSTITUTED POLY(ARYLENE VINYLENES), METHOD FOR PRODUCING THE SAME, AND THEIR USE IN ELECTROLUMINESCENT ELEMENTS | AXIVA GMBH (DE) | 1999-05-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030008884-A1 | Fungicidal phenyl (thio) urea and phenyl (thio) carbamate derivatives | NAT1, CAT, TPMT | CYP1A2 133/4885TSHR 1197/4885ALDH1A1 1599/4885 |
| US-12312363-B2 | Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-p53 inhibitors | TP53, MDM2, FOXM1 | CYP1A2 751/4885TSHR 1623/4885ALDH1A1 1055/4885 |
| US-20240109913-A1 | NEW SPIRO[3H-INDOLE-3,2'-PYRROLIDIN]-2(1H)-ONE COMPOUNDS AND DERIVATIVES AS MDM2-P53 INHIBITORS | TP53, MDM2, FOXM1 | CYP1A2 933/4885TSHR 1681/4885ALDH1A1 865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.