Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 4/20 | 0.39 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLA1 | P09884 | 1/20 | 0.37 |
| ▸ | HINT1 | P49773 | 1/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4499258 | 1.00 | KDM4E (0.54) | KDM4ETAS1R3TAS1R1HPGDALDH1A1 | |
| SCHEMBL25613003 | 1.00 | KDM4E (0.54) | KDM4ETAS1R3TAS1R1HPGDALDH1A1 | |
| SCHEMBL13626734 | 1.00 | KDM4E (0.54) | KDM4ETAS1R3TAS1R1HPGDALDH1A1 | |
| SCHEMBL13637338 | 1.00 | KDM4E (0.54) | KDM4ETAS1R3TAS1R1HPGDALDH1A1 | |
| SCHEMBL24181915 | 0.96 | KDM4E (0.56) | KDM4ETAS1R3TAS1R1HPGDALDH1A1 | |
| SCHEMBL26347587 | 0.96 | KDM4E (0.56) | KDM4ETAS1R3TAS1R1HPGDALDH1A1 | |
| SCHEMBL13626737 | 0.93 | KDM4E (0.48) | KDM4ETAS1R3TAS1R1HPGDALDH1A1 | |
| SCHEMBL26653707 | 0.93 | KDM4E (0.48) | KDM4ETAS1R3TAS1R1HPGDALDH1A1 | |
| SCHEMBL13637230 | 0.93 | KDM4E (0.48) | KDM4ETAS1R3TAS1R1HPGDALDH1A1 | |
| SCHEMBL25613001 | 0.92 | KDM4E (0.48) | KDM4ETAS1R3TAS1R1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220186217-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-06-16 | — | — | US | disclosed |
| US-20210254062-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2021-08-19 | — | — | US | disclosed |
| WO-2020118246-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2020-06-11 | — | — | WO | disclosed |
| WO-2019217784-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2019-11-14 | — | — | WO | disclosed |