SCHEMBL2156807

SCHEMBL2156807

CC(O)CN(CCO)CCN(CCN(CCO)CCO)CC(C)O

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.36
KDM4E B2RXH2 5/20 0.36
MAPT P10636 2/20 0.33
TSHR P16473 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
ALOX15 P16050 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
RECQL P46063 1/20 0.32
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
HPGD P15428 1/20 0.30
MAPK1 P28482 1/20 0.30
HIF1A Q16665 1/20 0.30
HSD17B10 Q99714 1/20 0.30
P2RX3 P56373 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30386839 1.00 TDP1 (0.36) TDP1KDM4EMAPTTSHRSMN1; SMN2
SCHEMBL10954251 1.00 TDP1 (0.36) TDP1KDM4EMAPTTSHRSMN1; SMN2
SCHEMBL10180673 0.95 TDP1 (0.36) TDP1KDM4EMAPTTSHRSMN1; SMN2
SCHEMBL344219 0.95 TDP1 (0.36) TDP1KDM4EMAPTTSHRSMN1; SMN2
Edetol SCHEMBL10874369 0.95 TDP1 (0.36) TDP1KDM4EMAPTTSHRSMN1; SMN2
SCHEMBL20994688 0.95 TDP1 (0.40) TDP1KDM4EMAPTTSHRSMN1; SMN2
SCHEMBL131477 0.95 TDP1 (0.40) TDP1KDM4EMAPTTSHRSMN1; SMN2
SCHEMBL4749725 0.93 KDM4E (0.35) TDP1KDM4EMAPTTSHRSMN1; SMN2
Trolamine SCHEMBL20421422 0.92 TDP1 (0.38) TDP1KDM4EMAPTTSHRALDH1A1
Hydrochloric Acid SCHEMBL29482287 0.92 KDM4E (0.41) TDP1KDM4EMAPTTSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8361220-B2 Strength improvement admixture CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2013-01-29 US claimed
US-20120298013-A1 Strength Improvement Admixture CONSTRUCTION RESEARCH & TECHNOLOGY GMBH 2012-11-29 US claimed
US-8258210-B2 Increasing compressive strength of cements without increasing setting time and polycarboxylic groups as dispersants CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2012-09-04 US claimed
EP-1603846-B1 STRENGTH IMPROVEMENT ADMIXTURE CONSTR RES & TECH GMBH (DE) 2012-07-11 EP claimed
US-7972435-B2 Amine containing strength improvement admixture CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2011-07-05 US claimed
US-20090292041-A1 AMINE CONTAINING STRENGTH IMPROVEMENT ADMIXTURE CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2009-11-26 US claimed
EP-1603846-A2 STRENGTH IMPROVEMENT ADMIXTURE Construction Research & Technology GmbH (DE) 2005-12-14 EP claimed
US-20050188896-A1 Amine containing strength improvement admixture CONSTRUCTION RESEARCH & TECHNOLOGY GMBH 2005-09-01 US claimed
US-20040198873-A1 Strength improvement admixture CONSTRUCTION RESEARCH AND TECHNOLOGY GMBH 2004-10-07 US claimed
WO-2004076376-A2 STRENGTH IMPROVEMENT ADMIXTURE CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2004-09-10 WO claimed
US-8361220-B2 Strength improvement admixture CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2013-01-29 US disclosed
US-20120298013-A1 Strength Improvement Admixture CONSTRUCTION RESEARCH & TECHNOLOGY GMBH 2012-11-29 US disclosed
US-8258210-B2 Increasing compressive strength of cements without increasing setting time and polycarboxylic groups as dispersants CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2012-09-04 US disclosed
EP-1603846-B1 STRENGTH IMPROVEMENT ADMIXTURE CONSTR RES & TECH GMBH (DE) 2012-07-11 EP disclosed
US-7972435-B2 Amine containing strength improvement admixture CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2011-07-05 US disclosed
US-20090292041-A1 AMINE CONTAINING STRENGTH IMPROVEMENT ADMIXTURE CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2009-11-26 US disclosed
US-7556684-B2 Amine containing strength improvement admixture CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2009-07-07 US disclosed
US-20050188896-A1 Amine containing strength improvement admixture CONSTRUCTION RESEARCH & TECHNOLOGY GMBH 2005-09-01 US disclosed
US-20040198873-A1 Strength improvement admixture CONSTRUCTION RESEARCH AND TECHNOLOGY GMBH 2004-10-07 US disclosed