Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 14/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23256879 | 0.89 | P2RY1 (0.50) | DYRK1AMAPTKMT2AP2RY1GSK3B | |
| SCHEMBL21568196 | 0.88 | P2RY1 (0.47) | DYRK1AMEN1KMT2AP2RY1GSK3B | |
| SCHEMBL21568098 | 0.87 | DYRK1A (0.46) | DYRK1AMAPTKMT2AP2RY1GSK3B | |
| SCHEMBL23256876 | 0.82 | MAPT (0.53) | DYRK1AMEN1LMNAPOLBMAPT | |
| SCHEMBL23256888 | 0.81 | NSD2 (0.53) | DYRK1AMEN1LMNAPOLBMAPT | |
| SCHEMBL21568376 | 0.81 | P2RY1 (0.43) | DYRK1AP2RY1GSK3BIRAK4P2RX1 | |
| SCHEMBL23256634 | 0.79 | P2RY1 (0.42) | DYRK1AP2RY1GSK3B | |
| SCHEMBL21569167 | 0.79 | CXCR2 (0.50) | DYRK1AMEN1LMNAPOLBMAPT | |
| SCHEMBL23256633 | 0.77 | P2RY1 (0.45) | MEN1POLBKMT2AP2RY1NPC1 | |
| SCHEMBL23256878 | 0.77 | CXCR2 (0.41) | DYRK1AMEN1KMT2AP2RY1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019217509-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | HB THERAPEUTICS INC. (US) | 2019-11-14 | — | — | WO | disclosed |