Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.59 |
| ▸ | ERBB2 | P04626 | 15/20 | 0.59 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.53 |
| ▸ | JAK3 | P52333 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21569004 | 0.96 | EGFR (0.57) | EGFRERBB2ERBB4JAK3 | |
| SCHEMBL14854799 | 0.91 | EGFR (0.72) | EGFRERBB2 | |
| SCHEMBL14854806 | 0.91 | EGFR (0.72) | EGFRERBB2 | |
| SCHEMBL14854804 | 0.91 | EGFR (0.72) | EGFRERBB2 | |
| SCHEMBL14854802 | 0.91 | EGFR (0.72) | EGFRERBB2 | |
| SCHEMBL21568968 | 0.90 | EGFR (0.67) | EGFRERBB2ERBB4JAK3 | |
| SCHEMBL21569100 | 0.90 | EGFR (0.67) | EGFRERBB2ERBB4JAK3 | |
| SCHEMBL21569086 | 0.90 | EGFR (0.67) | EGFRERBB2ERBB4JAK3 | |
| SCHEMBL21569010 | 0.89 | EGFR (0.60) | EGFRERBB2ERBB4 | |
| SCHEMBL21569035 | 0.89 | EGFR (0.58) | EGFRERBB2ERBB4JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3222620-B1 | CYANOQUINOLINE DERIVATIVES | TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO LTD (CN) | 2019-11-20 | — | — | EP | claimed |