Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 13/20 | 0.54 |
| ▸ | ACP1 | P24666 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23256548 | 0.86 | CSNK1D (0.61) | CSNK1DACP1DYRK1AALDH1A1CYP2D6 | |
| SCHEMBL21568186 | 0.84 | CSNK1D (0.51) | CSNK1DACP1DYRK1A | |
| SCHEMBL21568248 | 0.75 | CSNK1D (0.70) | CSNK1DACP1DYRK1ANPC1RAB9A | |
| SCHEMBL23256883 | 0.74 | DYRK1A (0.66) | CSNK1DDYRK1ANPC1ALDH1A1NFKB1 | |
| SCHEMBL21552285 | 0.74 | CSNK1D (0.60) | CSNK1DACP1DYRK1ANPC1RAB9A | |
| SCHEMBL21568075 | 0.73 | CSNK1D (0.59) | CSNK1DACP1DYRK1AALDH1A1CYP2D6 | |
| SCHEMBL23256882 | 0.73 | DYRK1A (0.58) | DYRK1ANPC1ALDH1A1NFKB1RAB9A | |
| SCHEMBL21568172 | 0.72 | DYRK1A (0.60) | CSNK1DACP1DYRK1ANPC1NFKB1 | |
| SCHEMBL21569134 | 0.72 | KDR (0.56) | CSNK1DACP1DYRK1ANPC1RAB9A | |
| SCHEMBL21568178 | 0.71 | CSNK1D (0.65) | CSNK1DACP1DYRK1ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019217509-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | HB THERAPEUTICS INC. (US) | 2019-11-14 | — | — | WO | disclosed |