Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 13/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 13/20 | 0.42 |
| ▸ | POLA1 | P09884 | 4/20 | 0.40 |
| ▸ | SOD1 | P00441 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21569787 | 0.93 | NR1H2 (0.46) | NR1H2NR1H3POLA1SOD1LMNA | |
| SCHEMBL21569982 | 0.91 | NR1H2 (0.54) | NR1H2NR1H3SOD1 | |
| SCHEMBL21569826 | 0.90 | NR1H2 (0.41) | NR1H2NR1H3POLA1PDE4D | |
| SCHEMBL21569769 | 0.90 | NR1H2 (0.42) | NR1H2NR1H3POLA1PDE4D | |
| SCHEMBL29292396 | 0.90 | NR1H2 (0.42) | NR1H2NR1H3POLA1PDE4D | |
| SCHEMBL29292353 | 0.90 | NR1H2 (0.41) | NR1H2NR1H3POLA1LMNACYP3A4 | |
| SCHEMBL21569788 | 0.90 | NR1H2 (0.53) | NR1H2NR1H3POLA1SOD1 | |
| SCHEMBL21570045 | 0.88 | NR1H2 (0.39) | NR1H2NR1H3POLA1 | |
| SCHEMBL21569768 | 0.88 | NR1H2 (0.40) | NR1H2NR1H3POLA1LMNACYP3A4 | |
| SCHEMBL21569814 | 0.86 | NR1H2 (0.39) | NR1H2NR1H3POLA1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019217591-A1 | ANTI-MSR1 ANTIBODIES AND METHODS OF USE THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2019-11-14 | — | — | WO | disclosed |