SCHEMBL2157232

SCHEMBL2157232

CCc1nccn1CCc1nc(N)nc(N)n1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.68
TLR8 Q9NR97 2/20 0.41
ALPG P10696 2/20 0.38
PLAA Q9Y263 1/20 0.38
ALPL P05186 1/20 0.37
CASP1 P29466 1/20 0.37
HRH4 Q9H3N8 2/20 0.37
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA3 P07451 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA13 Q8N1Q1 1/20 0.35
CA14 Q9ULX7 1/20 0.35
CA5B Q9Y2D0 1/20 0.35
CDK1 P06493 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25724015 0.84 TSHR (0.63) TSHRTLR8CASP1HRH4KCNH2
SCHEMBL10938676 0.84 TSHR (0.59) TSHRTLR8CASP1HRH4KCNH2
SCHEMBL821680 0.84 TSHR (0.59) TSHRTLR8CASP1HRH4KCNH2
SCHEMBL1695647 0.81 TSHR (1.00) TSHRTLR8ALPGPLAAALPL
SCHEMBL4592069 0.79 TLR8 (0.54) TSHRTLR8CASP1HRH4ALDH1A1
SCHEMBL11338048 0.77 TSHR (0.66) TSHRTLR8CASP1KCNH2SMN1; SMN2
SCHEMBL15252969 0.76 TSHR (0.55) TSHRCASP1HRH4ALDH1A1POLB
SCHEMBL2157582 0.75 TSHR (0.51) TSHRCASP1HRH4LMNASMN1; SMN2
SCHEMBL2792249 0.74 TLR8 (0.46) TSHRTLR8ALPGPLAAALPL
SCHEMBL15867746 0.74 TSHR (0.85) TSHRTLR8ALPGPLAAALPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1111972-B1 Flexible printed substrate SONY CHEM & INF DEVICE CORP (JP) 2007-05-23 EP claimed
CN-1213117-C Polyamide acid varnish compsns. and flexible printing base plate SONY CHEMICALS CO LTD (JP) 2005-08-03 CN claimed
US-20050027099-A1 Polyamic acid varnish composition and a flexible printed board SONY CHEMICALS CORP (JP) 2005-02-03 US claimed
US-6805967-B2 Polyamic acid varnish composition and a flexible printed board SONY CHEMICALS CORP. (JP) 2004-10-19 US claimed
EP-1108762-B1 Polyamic acid varnish composition and a flexible printed board SONY CHEMICALS CORP (JP) 2004-09-15 EP claimed
EP-1014765-B1 Flexible printed board, polyamic acid and polyamic acid varnish containing same SONY CHEMICALS CORP (JP) 2003-03-12 EP claimed
US-6395399-B2 METALLIC FOIL, E.G. COPPER, HAVING A POLYIMIDE LAYER PRODUCED BY FORMING A FILM OF A POLYAMIC ACID VARNISH FOLLOWED BY IMIDATING AND HAVING A SPECIFIC EXPANSION COEFFICIENT AND SOFTENING POINT; PRINTED CIRCUITS; NONCURLING SONY CHEMICALS CORP. (JP) 2002-05-28 US claimed
US-20010005730-A1 Polyamic acid varnish composition and a flexible printed board SONY CHEMICALS CORP. 2001-06-28 US claimed
EP-1111972-A2 Flexible printed substrate Sony Chemicals Corporation (JP) 2001-06-27 EP claimed
US-20010004496-A1 Flexible printed substrate SONY CHEMICALS CORP. 2001-06-21 US claimed
EP-1108762-A2 Polyamic acid varnish composition and a flexible printed board Sony Chemicals Corporation (JP) 2001-06-20 EP claimed
EP-1014765-A2 Flexible printed board, polyamic acid and polyamic acid varnish containing same Sony Chemicals Corporation (JP) 2000-06-28 EP claimed
US-4501689-A CONTAINING PYRIDINE OR IMIDAZOLE MODIFIED 5-TRIAZINE TAMURA KAKEN CO., LTD. (JP) 1985-02-26 US claimed
US-20230203353-A1 ADHESIVE FOR ENDOSCOPE AND CURED PRODUCT THEREOF, AND ENDOSCOPE AND METHOD FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2023-06-29 US disclosed
US-8986833-B2 Enamel varnish composition for enamel wire and enamel wire using same LS CABLE LTD. (KR) 2015-03-24 US disclosed
EP-1355518-B1 FLEXIBLE PRINTED WIRING BOARD SONY CHEM & INF DEVICE CORP (JP) 2013-09-25 EP disclosed
US-4129554-A PICRIC ACID, QUINONE, CHLORANIL, CYANOACETATE ESTER HITACHI CHEMICAL CO., LTD. (JP) 1978-12-12 US disclosed
US-4128531-A EPOXY, ISOCYANATE, CURING AGENT, HYDROXYLATED BUTADIENE POLYMER HITACHI CHEMICAL COMPANY, LTD. (JP) 1978-12-05 US disclosed
US-4070416-A POLYFUNCTIONAL ISOCYANATES AND EPOXIDES, ISOCYANURATE-OXAZOLIDOLE POLYMERS HITACHI, LTD. (JA) 1978-01-24 US disclosed
US-3979365-A FROM A POLYOXAZOLIDINE PREPOLYMER AND POLYISOCYANATE HITACHI, LTD. (JA) 1976-09-07 US disclosed