SCHEMBL2157244

SCHEMBL2157244

CC=CC(O)CN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2157237 1.00
SCHEMBL4178399 0.78
SCHEMBL4178398 0.78
SCHEMBL12321619 0.76
SCHEMBL5423894 0.74
SCHEMBL3861610 0.73
SCHEMBL9179759 0.73
SCHEMBL9179754 0.73
SCHEMBL12124671 0.73
SCHEMBL12122486 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7214738-B2 Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers ACUSHNET COMPANY (US) 2007-05-08 US claimed
US-20050009642-A1 Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US claimed
US-7973082-B2 Substituted aryloxy alkylamines and their use as monoamine neurotransmitter re-uptake inhibitors NEUROSEARCH A/S (DK) 2011-07-05 US disclosed
US-20090215905-A1 Novel substituted aryloxy alkylamines and their use as monoamine neurotransmitter re-uptake inhibitors ANIONA APS (DK) 2009-08-27 US disclosed
US-20090137342-A1 Golf Ball Layers Formed of Polyurethane-Based and Polyurea-Based Compositions Incorporating Block Copolymers ACUSHNET COMPANY 2009-05-28 US disclosed
US-7429629-B2 Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers ACUSHNET COMPANY (US) 2008-09-30 US disclosed
US-20070197724-A1 Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers ACUSHNET COMPANY 2007-08-23 US disclosed
US-7217764-B2 Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers ACUSHNET COMPANY (US) 2007-05-15 US disclosed
US-7214738-B2 Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers ACUSHNET COMPANY (US) 2007-05-08 US disclosed
US-7211624-B2 Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers ACUSHNET COMPANY (US) 2007-05-01 US disclosed
US-7202303-B2 Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers ACUSHNET COMPANY (US) 2007-04-10 US disclosed
US-20050009642-A1 Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US disclosed
US-20050009637-A1 Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US disclosed
US-20050009638-A1 Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US disclosed
US-20040262808-A1 Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-12-30 US disclosed
US-6509337-B1 A method of treating a mammalian disease condition mediated by metalloproteinase activity which comprises administering to a mammal in need thereof a therapeutically effective amount of a compound as defined in claim 1 or a pharmaceutically PFIZER INC. 2003-01-21 US disclosed
EP-0821671-B1 ARYLSULFONYL HYDROXAMIC ACID DERIVATIVES AS MMP AND TNF INHIBITORS PFIZER (US) 2000-12-27 EP disclosed
US-5861510-A Arylsulfonyl hydroxamic acid derivatives as MMP and TNF inhibitors PFIZER INC (US) 1999-01-19 US disclosed
EP-0821671-A1 ARYLSULFONYL HYDROXAMIC ACID DERIVATIVES AS MMP AND TNF INHIBITORS PFIZER INC. (US) 1998-02-04 EP disclosed
WO-1996033172-A1 ARYLSULFONYL HYDROXAMIC ACID DERIVATIVES AS MMP AND TNF INHIBITORS PFIZER INC. (US) 1996-10-24 WO disclosed