Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 19/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 19/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20392684 | 0.90 | ADORA2A (0.52) | ADORA2AADORA1ADORA2BMAP4K4 | |
| SCHEMBL21572891 | 0.90 | ADORA2A (0.40) | ADORA2AADORA1ADORA2BMAP4K4 | |
| SCHEMBL20392542 | 0.84 | ADORA2A (0.56) | ADORA2AADORA1ADORA2BMAP4K4 | |
| SCHEMBL20392756 | 0.77 | ADORA2A (0.57) | ADORA2AADORA1ADORA2B | |
| SCHEMBL20392601 | 0.75 | ADORA1 (0.56) | ADORA2AADORA1ADORA2B | |
| SCHEMBL20392760 | 0.74 | ADORA2A (0.62) | ADORA2AADORA1ADORA2B | |
| SCHEMBL20392686 | 0.74 | ADORA2A (0.59) | ADORA2AADORA1ADORA2BMAP4K4 | |
| SCHEMBL30738319 | 0.74 | ADORA2A (0.59) | ADORA2AADORA1ADORA2BMAP4K4 | |
| SCHEMBL20392590 | 0.74 | ADORA2A (0.59) | ADORA2AADORA1ADORA2BMAP4K4 | |
| SCHEMBL2325091 | 0.73 | ADORA2A (0.65) | ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3569596-A1 | 1,2,4-TRIAZINE-3-AMINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE | Jiangsu Hengrui Medicine Co. Ltd. (CN) | 2019-11-20 | — | — | EP | disclosed |