Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 15/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 14/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21572894 | 0.94 | ADORA2A (0.47) | ADORA2AADORA1ADORA2BMAP4K4ADORA3 | |
| SCHEMBL21577444 | 0.91 | ADORA2A (0.49) | ADORA2AADORA1ADORA2BMAP4K4ADORA3 | |
| SCHEMBL23692313 | 0.88 | ADORA2A (0.52) | ADORA2AADORA1ADORA2BMAP4K4ADORA3 | |
| SCHEMBL20392686 | 0.81 | ADORA2A (0.59) | ADORA2AADORA1ADORA2BMAP4K4ADORA3 | |
| SCHEMBL30738319 | 0.81 | ADORA2A (0.59) | ADORA2AADORA1ADORA2BMAP4K4ADORA3 | |
| SCHEMBL21577445 | 0.78 | ADORA2A (0.49) | ADORA2AADORA1ADORA2BMAP4K4ADORA3 | |
| SCHEMBL20392697 | 0.78 | ADORA2A (0.52) | ADORA2AADORA1ADORA2BMAP4K4ADORA3 | |
| SCHEMBL20392684 | 0.78 | ADORA2A (0.52) | ADORA2AADORA1ADORA2BMAP4K4ADORA3 | |
| SCHEMBL21569365 | 0.78 | ADORA2A (0.52) | ADORA2AADORA1ADORA2BMAP4K4ADORA3 | |
| SCHEMBL20392595 | 0.74 | ADORA2A (0.52) | ADORA2AADORA1ADORA2BMAP4K4ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3569596-A1 | 1,2,4-TRIAZINE-3-AMINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE | Jiangsu Hengrui Medicine Co. Ltd. (CN) | 2019-11-20 | — | — | EP | disclosed |