Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 18/20 | 0.76 |
| ▸ | VEGFA | P15692 | 6/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16560994 | 0.86 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL16560901 | 0.86 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL21004976 | 0.84 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL18036769 | 0.84 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL18036933 | 0.83 | VEGFA (0.80) | EPAS1VEGFA | |
| SCHEMBL16560910 | 0.83 | VEGFA (0.80) | EPAS1VEGFA | |
| SCHEMBL16560812 | 0.83 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL16555510 | 0.83 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL18036738 | 0.82 | VEGFA (1.00) | EPAS1VEGFA | |
| SCHEMBL16555912 | 0.82 | VEGFA (1.00) | EPAS1VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3043784-B9 | ARYL ETHERS AND USES THEREOF | PELOTON THERAPEUTICS INC (US) | 2019-11-20 | — | — | EP | disclosed |