Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 14/20 | 0.48 |
| ▸ | GAK | O14976 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14864911 | 0.88 | EGFR (0.52) | EGFRERBB2GAK | |
| SCHEMBL14864924 | 0.86 | EGFR (0.55) | EGFRERBB2GAK | |
| SCHEMBL14864912 | 0.85 | EGFR (0.66) | EGFRERBB2GAK | |
| SCHEMBL14856970 | 0.85 | EGFR (0.62) | EGFRERBB2 | |
| SCHEMBL14856972 | 0.85 | EGFR (0.62) | EGFRERBB2 | |
| SCHEMBL14856968 | 0.85 | EGFR (0.62) | EGFRERBB2 | |
| SCHEMBL14856971 | 0.85 | EGFR (0.62) | EGFRERBB2 | |
| SCHEMBL14864938 | 0.83 | EGFR (0.59) | EGFRERBB2GAK | |
| SCHEMBL14864919 | 0.81 | EGFR (0.66) | EGFRERBB2 | |
| SCHEMBL18933463 | 0.80 | EGFR (0.67) | EGFRERBB2GAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3222620-B1 | CYANOQUINOLINE DERIVATIVES | TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO LTD (CN) | 2019-11-20 | — | — | EP | disclosed |