Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 20/20 | 0.80 |
| ▸ | IDH2 | P48735 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29975762 | 0.89 | IDH1 (1.00) | IDH1IDH2 | |
| SCHEMBL16393229 | 0.89 | IDH1 (1.00) | IDH1IDH2 | |
| SCHEMBL22271138 | 0.88 | IDH1 (0.84) | IDH1IDH2 | |
| SCHEMBL16393297 | 0.86 | IDH1 (0.89) | IDH1IDH2 | |
| SCHEMBL29975197 | 0.86 | IDH1 (0.89) | IDH1IDH2 | |
| SCHEMBL16392857 | 0.84 | IDH1 (1.00) | IDH1IDH2 | |
| SCHEMBL21573340 | 0.82 | IDH1 (0.64) | IDH1IDH2 | |
| SCHEMBL16370080 | 0.82 | IDH1 (1.00) | IDH1IDH2 | |
| SCHEMBL16370154 | 0.82 | IDH1 (1.00) | IDH1IDH2 | |
| SCHEMBL16370749 | 0.82 | IDH1 (1.00) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019483-B1 | THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE | AGIOS PHARMACEUTICALS INC (US) | 2019-11-20 | — | — | EP | disclosed |