Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 20/20 | 0.87 |
| ▸ | IDH2 | P48735 | 3/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16393257 | 0.93 | IDH1 (1.00) | IDH1IDH2 | |
| SCHEMBL16392818 | 0.90 | IDH1 (1.00) | IDH1IDH2 | |
| SCHEMBL17971618 | 0.87 | IDH1 (0.87) | IDH1IDH2 | |
| SCHEMBL18557108 | 0.87 | IDH1 (0.87) | IDH1IDH2 | |
| SCHEMBL20210918 | 0.85 | IDH1 (0.79) | IDH1IDH2 | |
| SCHEMBL29763404 | 0.84 | IDH1 (0.82) | IDH1IDH2 | |
| SCHEMBL15094733 | 0.84 | IDH1 (0.82) | IDH1IDH2 | |
| SCHEMBL29560824 | 0.84 | IDH1 (0.82) | IDH1IDH2 | |
| SCHEMBL15094937 | 0.84 | IDH1 (0.82) | IDH1IDH2 | |
| SCHEMBL16392849 | 0.84 | IDH1 (1.00) | IDH1IDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307794-A | 1,3, 5-triazine derivatives and methods of use thereof | 正大天晴药业集团股份有限公司 | 2021-08-27 | — | — | CN | disclosed |
| CN-107922358-B | 1,3, 5-triazine derivatives and methods of use thereof | 正大天晴药业集团股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| EP-3019483-B1 | THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE | AGIOS PHARMACEUTICALS INC (US) | 2019-11-20 | — | — | EP | disclosed |