⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2655093 | 0.77 | — | — | |
| SCHEMBL2170868 | 0.71 | — | — | |
| SCHEMBL15726989 | 0.71 | — | — | |
| SCHEMBL1333591 | 0.68 | — | — | |
| SCHEMBL13632344 | 0.68 | — | — | |
| SCHEMBL25682846 | 0.67 | — | — | |
| SCHEMBL12890101 | 0.67 | — | — | |
| SCHEMBL17222770 | 0.66 | — | — | |
| SCHEMBL38659528 | 0.65 | — | — | |
| SCHEMBL20470805 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190352313-A1 | 1H-PYRROLE-2,5-DIONE COMPOUNDS AND METHODS OF USING THEM TO INDUCE SELF-RENEWAL OF STEM/PROGENITOR SUPPORTING CELLS | Frequency Therapeutics, Inc. | 2019-11-21 | — | — | US | disclosed |