Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9611663 | 0.84 | BTK (0.35) | BTKNFKB1NFKB2RELAKMT2A | |
| SCHEMBL15489159 | 0.84 | BTK (0.35) | BTKNFKB1NFKB2RELAKMT2A | |
| SCHEMBL13892845 | 0.82 | BTK (0.38) | BTKNFKB1NFKB2RELAKDM1A | |
| SCHEMBL15632420 | 0.82 | BTK (0.39) | BTKKMT2AL3MBTL1CTSKMEN1 | |
| SCHEMBL19508986 | 0.81 | GAA (0.39) | BTKNFKB1NFKB2RELAKMT2A | |
| SCHEMBL18256753 | 0.81 | GAA (0.39) | BTKNFKB1NFKB2RELAKMT2A | |
| SCHEMBL10108121 | 0.80 | BTK (0.35) | BTKNFKB1NFKB2RELAKMT2A | |
| SCHEMBL10108126 | 0.80 | BTK (0.35) | BTKNFKB1NFKB2RELAKMT2A | |
| SCHEMBL10329511 | 0.80 | BTK (0.47) | BTKKMT2AL3MBTL1GAAKDM1A | |
| SCHEMBL22233303 | 0.80 | EPHX1 (0.40) | BTKNFKB1NFKB2RELAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE47741-E1 | Antibacterial aminoglycoside analogs | ACHAOGEN, INC. (US) | 2019-11-26 | — | — | US | disclosed |