SCHEMBL21582019

SCHEMBL21582019

O=C(O)c1ncc(Cl)c(Cl)c1C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.44
MEN1 O00255 3/20 0.44
ALDH1A1 P00352 5/20 0.41
TDP1 Q9NUW8 3/20 0.41
ATM Q13315 1/20 0.38
DPP4 P27487 1/20 0.38
KDM4E B2RXH2 5/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
POLB P06746 1/20 0.36
RAB9A P51151 1/20 0.36
NAPRT Q6XQN6 1/20 0.35
KMO O15229 1/20 0.35
HPGD P15428 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HCAR2 Q8TDS4 1/20 0.34
LMNA P02545 1/20 0.34
HSD17B10 Q99714 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
ASPH Q12797 1/20 0.33
KDM8 Q8N371 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27963462 1.00 KMT2A (0.44) KMT2AMEN1ALDH1A1TDP1ATM
SCHEMBL27897786 0.98 KMT2A (0.43) KMT2AMEN1ALDH1A1TDP1ATM
SCHEMBL27880783 0.98 KMT2A (0.43) KMT2AMEN1ALDH1A1TDP1ATM
Methyl Alcohol SCHEMBL27889503 0.96 KMT2A (0.46) KMT2AMEN1ALDH1A1TDP1ATM
Methylamine SCHEMBL27839699 0.94 KMT2A (0.45) KMT2AMEN1ALDH1A1TDP1ATM
SCHEMBL28187503 0.93 KMT2A (0.40) KMT2AMEN1ALDH1A1TDP1ATM
Dimethylamine SCHEMBL27801006 0.93 KMT2A (0.44) KMT2AMEN1ALDH1A1TDP1ATM
Dimethylamine SCHEMBL29642928 0.93 KMT2A (0.44) KMT2AMEN1ALDH1A1TDP1ATM
Alcohol SCHEMBL28161283 0.91 TDP1 (0.46) KMT2AMEN1ALDH1A1TDP1ATM
Isopropylamine SCHEMBL27857515 0.89 KMT2A (0.41) KMT2AMEN1ALDH1A1TDP1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3527 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107868047-B Method for preparing quinclorac through catalytic oxidation 南京工业大学 2023-03-21 CN claimed
CN-115025821-A Hydrothermal carbon composite material, preparation method thereof, catalytic system and application 湖南农业大学 2022-09-09 CN claimed
CN-112390752-B Chloromethylquinolinic acid and its preparing method 北京颖泰嘉和生物科技股份有限公司 2022-08-26 CN claimed
CN-114885952-A Novel herbicidal compounds 马罗内生物创新公司 2022-08-12 CN claimed
CN-111246740-B Novel herbicidal compounds 马罗内生物创新公司 2022-06-10 CN claimed
CN-113453553-A Herbicidal composition 先正达农作物保护股份公司 2021-09-28 CN claimed
CN-109212108-B Gas chromatography-mass spectrometry combined method for simultaneously determining three trace quinoline herbicides in rice and soybean 丁立平 2021-05-07 CN claimed
CN-106305178-B A kind of comprehensive method for improving tobacco field weeding and tobacco seedlings disease resistance and reduce teratogenesis generation 中国烟草总公司广东省公司 2019-12-03 CN claimed
CN-110495362-A A kind of Integrated co ntrol method of weeds in paddy field SHANGHAI ACAD AGRI SCIENCES 2019-11-26 CN claimed
CN-105198861-B 6- acyl group -1,2,4- triazine -3,5- derovatives and herbicide FMC公司 2019-11-22 CN claimed
CN-1252218-A Floating agricultural chemical preparation for rice field and its preparing process CHANGSHA INST OF MINING & META (CN) 2000-05-10 CN claimed
CN-1234176-A Effervescence farm-chemical composition and production method thereof ECOLOGICAL ENVIRONMENT RESEARC (CN) 1999-11-10 CN claimed
CN-1218620-A Rice field herbicide containing azethapyr and pyrazosulfuron STATE RUN KUNSHAN CHEMICAL PLA (CN) 1999-06-09 CN claimed
CN-1200652-A Herbicidal mixtures with synergistic activity BASF AG (DE) 1998-12-02 CN claimed
CN-1200649-A Synergistic herbicidal mixtures comprising cyclohexenone oxime ethers BASF AG (DE) 1998-12-02 CN claimed
CN-1191071-A Dichloroquinolinic acid suspending agent XINYI AGROCHEM EX BASE JIANGSU (CN) 1998-08-26 CN claimed
CN-1183217-A Propisochlor (propiochlor) -containing herbicidal composition YOU ZHENGUO (CN) 1998-06-03 CN claimed
CN-1160483-A Rice seedling-throwing agent UNITED XINYI AGROCHEMICAL EX B (CN) 1997-10-01 CN claimed
CN-1108882-A High effective and broad spectrum herbicide for rice field LOUDI GRAINS AND OILS SCIENCE (CN) 1995-09-27 CN claimed
CN-1104847-A Disposable \"Daofujing\" herbicide for rice field SHENYANG CHEMICAL INST MINISTR (CN) 1995-07-12 CN claimed