Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.69 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.69 |
| ▸ | ADORA2B | P29275 | 11/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21583403 | 0.85 | ADORA2A (0.63) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL29502749 | 0.82 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B | |
| SCHEMBL21581767 | 0.82 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B | |
| SCHEMBL11146964 | 0.80 | ADORA2A (0.67) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL21581752 | 0.78 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B | |
| SCHEMBL29502730 | 0.78 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B | |
| SCHEMBL21581753 | 0.76 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B | |
| SCHEMBL21581773 | 0.76 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B | |
| SCHEMBL21581772 | 0.76 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B | |
| SCHEMBL29502728 | 0.76 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3575301-A1 | HETEROARYL[4,3-C]PYRIMIDINE-5-AMINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USES THEREOF | Jiangsu Hengrui Medicine Co., Ltd. (CN) | 2019-12-04 | — | — | EP | disclosed |