Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.57 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.57 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.54 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.54 |
| ▸ | ITGAL | P20701 | 2/20 | 0.54 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.46 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23221680 | 1.00 | ITGB1 (0.57) | ITGB1ITGA4ITGB2ICAM1ITGAL | |
| SCHEMBL21583785 | 0.89 | PSMB5 (0.50) | ITGB1ITGA4ITGB2ICAM1ITGAL | |
| SCHEMBL21581968 | 0.84 | ITGB1 (0.67) | ITGB1ITGA4ITGB2ICAM1ITGAL | |
| SCHEMBL21581967 | 0.84 | ITGB1 (0.67) | ITGB1ITGA4ITGB2ICAM1ITGAL | |
| SCHEMBL23201831 | 0.82 | PSMB5 (0.66) | ITGB1ITGA4ITGB2ICAM1ITGAL | |
| SCHEMBL23201830 | 0.82 | PSMB5 (0.66) | ITGB1ITGA4ITGB2ICAM1ITGAL | |
| SCHEMBL27607610 | 0.77 | ITGB1 (0.60) | ITGB1ITGA4PSMB5LMNAHPGD | |
| SCHEMBL27607611 | 0.77 | ITGB1 (0.60) | ITGB1ITGA4PSMB5LMNAHPGD | |
| SCHEMBL5927201 | 0.75 | ITGB1 (0.66) | ITGB1ITGA4PSMB5MCL1MRGPRX4 | |
| SCHEMBL8337586 | 0.73 | ITGB1 (0.66) | ITGB1ITGA4PSMB5MCL1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11542283-B2 | Synthesis of peptide borate ester compound and use thereof | JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. (CN) | 2023-01-03 | — | — | US | disclosed |
| US-20210214377-A1 | SYNTHESIS OF PEPTIDE BORATE ESTER COMPOUND AND USE THEREOF | JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. (CN) | 2021-07-15 | — | — | US | disclosed |
| EP-3805237-A1 | SYNTHESIS AND USES OF PEPTIDE BORATE ESTER COMPOUND | Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd. (CN) | 2021-04-14 | — | — | EP | disclosed |
| WO-2019228299-A1 | SYNTHESIS AND USES OF PEPTIDE BORATE ESTER COMPOUND | 江苏正大丰海制药有限公司 (CN) | 2019-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210214377-A1 | SYNTHESIS OF PEPTIDE BORATE ESTER COMPOUND AND USE THEREOF | SEM1, VIP, PSMB11 | ITGB1 4133/4885ITGA4 4362/4885ITGB2 4448/4885 |
| US-11542283-B2 | Synthesis of peptide borate ester compound and use thereof | SEM1, VIP, PSMB11 | ITGB1 4133/4885ITGA4 4362/4885ITGB2 4448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.