Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22476251 | 1.00 | NR1H4 (0.36) | NR1H4SLC10A2 | |
| SCHEMBL28530679 | 0.93 | NR1H4 (0.37) | NR1H4SLC10A2 | |
| SCHEMBL21585960 | 0.93 | NR1H4 (0.37) | NR1H4SLC10A2 | |
| SCHEMBL21585999 | 0.92 | NR1H4 (0.40) | NR1H4 | |
| SCHEMBL22476235 | 0.92 | NR1H4 (0.40) | NR1H4 | |
| SCHEMBL23451427 | 0.92 | NR1H4 (0.35) | NR1H4SLC10A2 | |
| SCHEMBL22476264 | 0.92 | NR1H4 (0.35) | NR1H4 | |
| SCHEMBL21585954 | 0.92 | NR1H4 (0.40) | NR1H4 | |
| SCHEMBL21585956 | 0.92 | NR1H4 (0.40) | NR1H4 | |
| SCHEMBL29189012 | 0.92 | NR1H4 (0.34) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802504-A1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | Albireo AB (SE) | 2021-04-14 | — | — | EP | disclosed |
| CN-112449637-A | Benzothia (di) azepanes and their use as bile acid modulators | 阿尔比里奥公司 | 2021-03-05 | — | — | CN | disclosed |
| WO-2019234077-A1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2019-12-12 | — | — | WO | disclosed |