Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22476191 | 1.00 | NR1H4 (0.34) | NR1H4 | |
| SCHEMBL28530434 | 0.94 | NR1H4 (0.33) | NR1H4 | |
| SCHEMBL21586003 | 0.93 | NR1H4 (0.35) | NR1H4 | |
| SCHEMBL21586004 | 0.93 | NR1H4 (0.35) | NR1H4 | |
| SCHEMBL28530347 | 0.89 | NR1H4 (0.34) | NR1H4 | |
| SCHEMBL22476183 | 0.89 | NR1H4 (0.34) | NR1H4 | |
| SCHEMBL23451427 | 0.89 | NR1H4 (0.35) | NR1H4 | |
| SCHEMBL21585999 | 0.89 | NR1H4 (0.40) | NR1H4 | |
| SCHEMBL22476264 | 0.89 | NR1H4 (0.35) | NR1H4 | |
| SCHEMBL22476235 | 0.89 | NR1H4 (0.40) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802504-A1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | Albireo AB (SE) | 2021-04-14 | — | — | EP | disclosed |
| WO-2019234077-A1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2019-12-12 | — | — | WO | disclosed |