Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C2A | O00443 | 15/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.58 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21589381 | 0.88 | PIK3C2A (0.67) | PIK3C2AALDH1A1ALOX15LMNAPIK3C2B | |
| SCHEMBL21586285 | 0.87 | PIK3C2A (0.75) | PIK3C2AALDH1A1ALOX15LMNAPIK3C2B | |
| SCHEMBL30002990 | 0.83 | PIK3C2A (1.00) | PIK3C2AALDH1A1ALOX15LMNAPIK3C2B | |
| SCHEMBL21586351 | 0.83 | PIK3C2A (1.00) | PIK3C2AALDH1A1ALOX15LMNAPIK3C2B | |
| SCHEMBL27224597 | 0.83 | PIK3C2A (0.72) | PIK3C2AALDH1A1ALOX15LMNAPIK3C2B | |
| SCHEMBL21589383 | 0.83 | PIK3C2A (0.72) | PIK3C2AALDH1A1ALOX15LMNAPIK3C2B | |
| SCHEMBL21586313 | 0.80 | PIK3C2A (1.00) | PIK3C2APIK3C2BPIK3C2GHSD17B10 | |
| SCHEMBL30003412 | 0.80 | PIK3C2A (1.00) | PIK3C2APIK3C2BPIK3C2GHSD17B10 | |
| SCHEMBL21586352 | 0.78 | PIK3C2A (1.00) | PIK3C2AALDH1A1ALOX15LMNAPIK3C2B | |
| SCHEMBL30003900 | 0.78 | PIK3C2A (1.00) | PIK3C2AALDH1A1ALOX15LMNAPIK3C2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802530-B1 | HETEROCYCLIC COMPOUNDS AS CLASS II PHOSPHOINOSITIDE 3-KINASE INHIBITORS | FORSCHUNGSVERBUND BERLIN EV (DE) | 2024-05-29 | — | — | EP | disclosed |
| EP-3802530-A1 | HETEROCYCLIC COMPOUNDS AS CLASS II PHOSPHOINOSITIDE 3-KINASE INHIBITORS | Forschungsverbund Berlin E.V. (DE) | 2021-04-14 | — | — | EP | disclosed |
| WO-2019234237-A1 | HETEROCYCLIC COMPOUNDS AS CLASS II PHOSPHOINOSITIDE 3-KINASE INHIBITORS | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2019-12-12 | — | — | WO | disclosed |